Probiotics: Bifidobacterium longum subsp. longum BB536 (Bifidus BB536)

Bifidobacterium longum subsp. longum BB536 is a well-documented probiotic strain known for its gut health benefits, immune system support, and anti-inflammatory properties. It is widely used in dietary supplements and functional foods to promote digestive balance, enhance immunity, and improve overall well-being.
What is Bifidobacterium longum subsp. longum BB536?
Bifidobacterium longum BB536 is a clinically studied probiotic strain originally isolated from healthy infants. It is one of the most extensively researched probiotic strains, with over 50 years of scientific studies supporting its gut microbiome-enhancing, immune-modulating, and anti-inflammatory effects. BB536 colonizes the intestines effectively, promoting beneficial bacteria growth and inhibiting harmful pathogens.
Health Benefits of Bifidobacterium longum BB536
- Promotes Digestive Health and Gut Microbiome Balance
BB536 enhances beneficial gut bacteria populations while reducing harmful microorganisms, supporting optimal digestion and intestinal function. It also helps relieve bloating, constipation, and diarrhea. - Supports Immune System Function
Clinical studies show that BB536 enhances the body’s natural immune defenses by stimulating the production of immune cells and improving gut-associated lymphoid tissue (GALT) function. - Reduces Inflammation and Supports Gut Barrier Integrity
BB536 has anti-inflammatory effects, helping to maintain a healthy gut lining and prevent conditions like leaky gut syndrome, irritable bowel syndrome (IBS), and inflammatory bowel disease (IBD). - Alleviates Allergy Symptoms and Supports Respiratory Health
BB536 has been studied for its role in reducing seasonal allergies by modulating immune responses, particularly in individuals with hay fever (allergic rhinitis). It also supports respiratory health by improving immune resilience. - Supports Healthy Aging and Metabolic Health
By promoting a well-balanced gut microbiome, BB536 supports metabolic function, helps regulate cholesterol levels, and contributes to overall longevity.
Scientific Support
- Gut Microbiome Balance & Digestive Health: BB536 improves gut flora composition, reduces bloating, and alleviates constipation (Takeda et al., 2022).
- Immune Function Enhancement: Increases immune cell activity and enhances gut immunity (Wong et al., 2019).
- Anti-Inflammatory & Gut Barrier Support: Reduces intestinal inflammation and supports gut lining integrity (Yao et al., 2021).
- Allergy Relief & Respiratory Health: Helps manage allergic rhinitis and reduces seasonal allergy symptoms (Luo et al., 2022).
- Metabolic & Aging Support: Modulates cholesterol levels and promotes longevity (Mills et al., 2023).