Gut Health

Postbiotics: Limosilactobacillus reuteri DSM 17648 (Pylopass™)

Limosilactobacillus reuteri DSM 17648 is a postbiotic strain known for its oral health benefits, antibacterial activity against harmful oral bacteria, and potential gut health support. It has been widely studied for its role in promoting dental and gum health, reducing harmful bacterial load in the mouth, and supporting overall microbiome balance.

What is Limosilactobacillus reuteri DSM 17648?

Limosilactobacillus reuteri DSM 17648 is a specific strain of L. reuteri that has been inactivated but retains its beneficial bioactive properties. This postbiotic is known for its ability to target and bind to harmful oral bacteria, particularly those associated with plaque buildup, gum inflammation, and bad breath (halitosis).

Unlike probiotics, postbiotics like L. reuteri DSM 17648 do not require live bacteria to be effective, making them more stable and suitable for supplementation.

Health Benefits of Limosilactobacillus reuteri DSM 17648

  1. Promotes Oral and Gum Health
    L. reuteri DSM 17648 selectively binds to and reduces harmful bacteria like Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, which are linked to gingivitis and periodontitis. This supports overall gum health and reduces inflammation.
  2. Reduces Plaque Formation and Supports Dental Hygiene
    By inhibiting plaque-forming bacteria, this strain helps maintain cleaner teeth and reduces the risk of cavities and tartar buildup.
  3. Combats Bad Breath (Halitosis)
    L. reuteri DSM 17648 helps neutralize odor-causing bacteria in the mouth, reducing bad breath and promoting a fresher oral environment.
  4. Supports Gut Health and Microbiome Balance
    Though primarily known for its oral health benefits, studies suggest L. reuteri strains can also support a balanced gut microbiome, contributing to digestive health and immune function.
  5. Non-Live Stability for Effective Supplementation
    As a postbiotic, L. reuteri DSM 17648 is more stable than live probiotics, making it ideal for chewable tablets, lozenges, and oral health supplements.

Scientific Support

  1. Oral Health & Gum Support: L. reuteri DSM 17648 reduces harmful oral bacteria associated with periodontitis and plaque formation (Ananda et al., 2024).
  2. Plaque Reduction & Dental Hygiene: Studies show a significant decrease in plaque accumulation with L. reuteri supplementation (Ananda et al., 2024).
  3. Bad Breath Reduction: Postbiotic action helps neutralize odor-causing bacteria, improving breath freshness (Ananda et al., 2024).
  4. Gut Microbiome & Digestive Health: L. reuteri strains contribute to a balanced gut environment and improved immune response (Ananda et al., 2024).

References

https://pmc.ncbi.nlm.nih.gov/articles/PMC10905032