GABA – F95R(200526) Japan patent: 2810993 (Oryza GABA)

Gamma-Aminobutyric Acid (GABA) is a naturally occurring neurotransmitter that plays a crucial role in relaxation, stress reduction, and cognitive function. It is widely recognized for its ability to promote calmness, improve sleep quality, and enhance mental focus. GABA also influences blood pressure regulation, muscle recovery, and overall nervous system balance.

The F95R(200526) formulation, covered under Japan Patent 2810993, ensures a highly bioavailable and stable form of GABA, allowing for enhanced absorption and effectiveness in stress management and physiological regulation.

What is GABA?

GABA is the primary inhibitory neurotransmitter in the central nervous system, responsible for reducing neuronal excitability and promoting a state of calmness. It counterbalances stimulatory neurotransmitters like glutamate, helping regulate mood, sleep, and cognitive function.

While the body naturally produces GABA, supplementation is beneficial for individuals experiencing stress, anxiety, insomnia, or cognitive fatigue, as it helps restore balance to the nervous system.

Health Benefits of GABA

1. Promotes Relaxation and Reduces Stress
   GABA plays a key role in calming the nervous system by reducing excessive neural activity, which helps alleviate stress, tension, and anxiety. Studies show that GABA supplementation can lower cortisol levels, the primary stress hormone, and increase alpha brain waves, which are associated with relaxation.
2. Improves Sleep Quality
   By inhibiting excitatory signals in the brain, GABA helps reduce nighttime restlessness and enhances deep sleep cycles. Individuals with insomnia or irregular sleep patterns benefit from GABA’s ability to induce a faster onset of sleep and improve overall sleep duration and quality.
3. Enhances Cognitive Function and Focus
   Balanced GABA levels contribute to better concentration, memory, and mental clarity. It helps prevent overstimulation of neurons, which can otherwise lead to mental fatigue or cognitive burnout. Research suggests that GABA supplementation supports better attention span and learning efficiency.
4. Supports Blood Pressure Regulation
   GABA has been shown to promote vascular relaxation and improved circulation, helping to lower high blood pressure and support cardiovascular health. Its calming effect on the nervous system may contribute to better heart rate variability and reduced risk of hypertension-related complications.
5. Aids in Muscle Recovery and Physical Performance
   GABA is involved in growth hormone release, which supports muscle recovery, repair, and overall physical endurance. Athletes and individuals engaging in regular exercise may benefit from improved muscle recovery, reduced fatigue, and enhanced strength gains.
6. Neuroprotective Benefits for Brain Health
   GABA helps maintain neurological balance and is being studied for its potential role in neurodegenerative disorders, such as Alzheimer’s and Parkinson’s disease. Its ability to protect neurons from overstimulation and oxidative stress makes it a promising compound for long-term brain health.

The F95R(200526) Formulation and Japan Patent 2810993

This patented formulation ensures enhanced bioavailability and stability of GABA, allowing for faster absorption and greater effectiveness in stress reduction, cognitive support, and blood pressure regulation. The advanced processing method optimizes purity and potency, making it more efficient compared to standard GABA supplements.
GABA – F95R(200526) is a potent neurotransmitter supplement that supports relaxation, sleep quality, cognitive function, cardiovascular health, and muscle recovery, making it a valuable addition to overall wellness.

Scientific Support

1. Stress & Relaxation: GABA supplementation lowers cortisol and increases alpha wave activity (Liwinski et al., 2023).
2. Sleep Quality: Improves sleep onset and deep sleep cycles (Varinthra et al., 2024).
3. Cognitive Function: Enhances focus and prevents mental fatigue (Lim et al., 2021).
4. Blood Pressure Regulation: Lowers hypertension risk through vascular relaxation (Ma et al., 2015).
5. Muscle Recovery: Increases growth hormone secretion and reduces exercise-induced fatigue (Sakashita et al., 2019).
6. Neuroprotection: Helps maintain neural stability and may protect against neurodegenerative diseases (Kim et al., 2017).

References

1. https://pmc.ncbi.nlm.nih.gov/articles/PMC10741010/
2. https://pmc.ncbi.nlm.nih.gov/articles/PMC11025592/
3. https://pmc.ncbi.nlm.nih.gov/articles/PMC8122390/
4. https://pmc.ncbi.nlm.nih.gov/articles/PMC4613098/
5. https://pmc.ncbi.nlm.nih.gov/articles/PMC6522239/
6. https://pmc.ncbi.nlm.nih.gov/articles/PMC5696856/