Cardiometabolic Health, Cognitive Health

Free lutein and zeaxanthin (XanMax®)

Lutein and zeaxanthin are powerful carotenoids that play a critical role in eye health, cognitive function, and overall antioxidant protection. These naturally occurring pigments are found in leafy greens, egg yolks, and certain vegetables, and they accumulate in the retina and brain, offering protection against oxidative damage, blue light exposure, and age-related degeneration.

What Are Free Lutein and Zeaxanthin?

Lutein and zeaxanthin are xanthophyll carotenoids, meaning they have strong antioxidant and light-filtering properties. They are structurally similar but have distinct roles in protecting vision and cognitive function. Free-form lutein and zeaxanthin are the most bioavailable versions, allowing for better absorption and utilization in the body compared to esterified forms.

These carotenoids are concentrated in the macula of the eye, where they form the macular pigment that helps filter harmful blue light, reduce oxidative stress, and prevent vision decline. Additionally, they accumulate in the brain, supporting cognitive health and neuroprotection.

Health Benefits of Free Lutein and Zeaxanthin

  1. Supports Eye Health and Protects Against Age-Related Vision Loss
    Lutein and zeaxanthin are essential for maintaining healthy vision by protecting the retina from oxidative damage and harmful blue light exposure. Studies show they reduce the risk of age-related macular degeneration (AMD) and cataracts by strengthening macular pigment density.
  2. Filters Harmful Blue Light and Reduces Eye Strain
    With increased screen exposure, blue light damage has become a concern. Lutein and zeaxanthin act as natural blue light filters, reducing digital eye strain, glare sensitivity, and potential long-term retinal damage.
  3. Enhances Cognitive Function and Brain Health
    These carotenoids accumulate in the brain, where they play a role in cognitive performance, memory, and neural efficiency. Studies suggest that higher lutein and zeaxanthin levels are associated with better cognitive function, slower cognitive decline, and improved processing speed in aging individuals.
  4. Powerful Antioxidant Protection
    Lutein and zeaxanthin neutralize free radicals and reduce oxidative stress, helping protect the eyes, brain, skin, and cardiovascular system from age-related damage and inflammation.
  5. Supports Skin Health and UV Protection
    By reducing oxidative stress in skin cells, these carotenoids help protect against UV-induced damage, reducing the risk of premature aging, sun spots, and wrinkles.
  6. Promotes Cardiovascular Health
    Research indicates that lutein may reduce arterial stiffness, lower inflammation, and improve circulation, contributing to better heart health and reduced risk of cardiovascular disease.

Scientific Support

  1. Eye Health & Macular Degeneration: Improves macular pigment density and reduces AMD risk (Mrowicka et al., 2022).
  2. Blue Light Protection: Acts as a natural filter against harmful light exposure (Roberts et al., 2015).
  3. Cognitive Function & Brain Health: Enhances memory, processing speed, and cognitive resilience (Parekh et al., 2024).
  4. Antioxidant & Anti-Inflammatory Properties: Protects against oxidative stress and cellular damage (Anh et al., 2021).
  5. Skin & UV Protection: Reduces sun-induced skin aging and protects skin cells from damage (Mrowicka et al., 2022).
  6. Cardiovascular Health: Lowers arterial inflammation and improves circulation (Anh et al., 2021).

References

  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC8874683/
  2. https://pmc.ncbi.nlm.nih.gov/articles/PMC4698938/
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC10960892/
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC8470349/
  5. https://pmc.ncbi.nlm.nih.gov/articles/PMC8874683/
  6. https://pmc.ncbi.nlm.nih.gov/articles/PMC8470349/