Liver Health, Mental Health

L-Ornithine monohydrate

L-Ornithine Monohydrate is a non-essential amino acid involved in the urea cycle, helping to detoxify ammonia from the body. It plays a crucial role in liver function, athletic performance, muscle recovery, and sleep quality.

What is L-Ornithine Monohydrate?

L-Ornithine is a naturally occurring amino acid that does not directly participate in protein synthesis but serves as a precursor to other important compounds, including arginine, citrulline, and polyamines. It is commonly used to enhance liver detoxification, reduce fatigue, and support muscle recovery. The monohydrate form improves solubility and absorption, making it more bioavailable for supplementation.

Health Benefits of L-Ornithine Monohydrate

  1. Supports Liver Detoxification and Ammonia Clearance
    L-Ornithine plays a key role in the urea cycle, helping the liver convert toxic ammonia into urea, which is then excreted through urine. This process is essential for maintaining nitrogen balance and preventing ammonia buildup, which can cause fatigue and cognitive impairment.
  2. Enhances Athletic Performance and Muscle Recovery
    Ornithine supplementation has been shown to reduce muscle fatigue and improve endurance by lowering ammonia levels during exercise. It supports protein metabolism and energy production, making it beneficial for athletes and active individuals.
  3. Improves Sleep Quality and Reduces Stress
    Studies suggest that L-Ornithine helps reduce cortisol levels, promoting relaxation and better sleep quality. It may also enhance recovery from physical and mental stress, contributing to overall well-being and cognitive function.
  4. Supports Wound Healing and Tissue Repair
    Ornithine is involved in the production of polyamines, which are essential for cell growth, tissue regeneration, and wound healing. This makes it beneficial for post-surgical recovery and injury repair.
  5. May Help in Liver Health and Fatigue Reduction
    L-Ornithine has been studied for its potential to support individuals with liver disorders, particularly those with hepatic encephalopathy, a condition caused by excessive ammonia levels. It may also reduce general fatigue in people experiencing chronic stress or physical exertion.

Scientific Support

  1. Liver Detoxification & Ammonia Clearance: Enhances ammonia elimination and supports liver function (Canbay et al., 2019).
  2. Athletic Performance & Muscle Recovery: Reduces exercise-induced fatigue and enhances endurance (Demura et al., 2010).
  3. Sleep Quality & Stress Reduction: Lowers cortisol levels and promotes relaxation (Miyake et al., 2014).
  4. Wound Healing & Tissue Repair: Stimulates polyamine synthesis for cell regeneration (Chow et al., 2014).
  5. Liver Health & Fatigue Reduction: Beneficial for individuals with hepatic conditions and general fatigue (Goh et al., 2018).

References

  1. https://pmc.ncbi.nlm.nih.gov/articles/PMC6416231/
  2. https://pubmed.ncbi.nlm.nih.gov/20717126/
  3. https://pmc.ncbi.nlm.nih.gov/articles/PMC4055948/
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC3900114/
  5. https://pmc.ncbi.nlm.nih.gov/articles/PMC6494563/